ConoDictor

Prediction and classification of conopeptides from cone snail venom gland transcriptomes, proteomes and peptides.

For every sequence, ConoDictor 3 gives:

• the probability of each gene superfamily and of NONE (not a conopeptide);
• the best superfamily if the sequence is known to be a conopeptide (e.g. from peptidomics);
• the precursor regions (signal peptide, propeptide, mature peptide), the mature peptide, its cysteine framework and predicted C-terminal amidation.

Input: protein or nucleotide FASTA/FASTQ (reads, contigs, ORFs), plain or compressed. The reference database (conodictor-db-2026_04, 18 superfamilies) is rebuilt from UniProtKB with conodb.

Run ConoDictor How it works

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How to cite us

Koua D, Ebou A, Dutertre S. (2021)
Improved prediction of conopeptide superfamilies with ConoDictor 2.0. Bioinformatics Advances, 10.1093/bioadv/vbab011

Koua D, Brauer A, Laht S, Kaplinski L, Favreau P, Remm M, Lisacek F, Stöcklin R. (2012)
ConoDictor: a tool for prediction of conopeptide superfamilies. Nucleic Acids Research, 10.1093/nar/gks337