Reference database

conodictor-db-2026_04, built from UniProtKB release 2026_04 by conodb 0.1.0.

The database is rebuilt from UniProtKB/Swiss-Prot with conodb: reviewed Conus conopeptide precursors, curated superfamily labels, entries grouped at 70% identity so that no near-duplicate is shared between training and evaluation, region profiles (HMM, PSSM, position weight matrices), full-precursor models for region prediction, and a multinomial classifier with a NONE class trained against non-conopeptide secreted proteins and shuffled precursors.

Superfamilies (18)
SuperfamilyMature peptides in the database
A201
B14
C18
Con-insulin50
D33
H5
I138
I232
I38
J8
L8
M187
O1289
O2113
O322
P8
S9
T154

Classifier features: SIG:hmm, SIG:pssm, SIG:pwm, PRO:hmm, PRO:pssm, PRO:pwm, MAT:hmm, MAT:pssm, MAT:pwm, FW:framework.

Every release, its evaluation and the tables behind it are archived on Zenodo; the evaluation, benchmark and supplementary tables are listed in the paper.